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KMID : 0603820170230020111
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Journal of Experimental & Biomedical Science
2017 Volume.23 No. 2 p.111 ~ p.117
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Comparison of Efficiency between Pre-storage and Post-storage filtration by Leukoreduction Blood Filter
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Shin Geon-Sik
Kim Bo-Hee
Kim Sung-Hoon
Rhee Ki-Jong
Kim Yoon-Suk
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Abstract
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Leukocytes in blood components are involved in diverse adverse transfusion reactions such as febrile non-hemolytic transfusion reactions. Therefore, leukocyte reduction is required to reduce these adverse reactions. The objective of this study was to compare the efficiency of pre-storage filtration and post-storage filtration. Filtration time, residual leukocyte count, RBC recovery, and hemolysis were assessed after pre-storage or post-storage filtration. Compared to pre-storage filtration, filtration time was prolonged and hemolysis was dramatically increased when post-storage filtration was performed. Residual leukocytes count and RBC recovery after post-storage filtration were similar with those obtained after pre-storage filtration. These results suggest that pre-storage filtration has better efficiency than post-storage filtration. These are thought to contribute to the production of better quality of leukoreduction blood components.
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KEYWORD
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Leukoreduction blood filter , Adverse transfusion reaction , Pre-storage filtration , Filtration efficiency
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Listed journal information
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